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Usbsid-Pico: Bridging Real Commodore 64 Sound to Modern USB

2026-09-03 @ 17:09:04Points: 13Comments: 4

Founding Creative Engineer – Gooseworks (YC W23) Is Hiring

2026-09-03 @ 17:00:16Points: 1

Launch HN: Mireye (YC S26) – Infrastructure for Physical World AI Agents

2026-09-03 @ 16:24:13Points: 22Comments: 1

https://www.mireye.com). I'm building the infrastructure AI agents use to make decisions about physical places: data, enrichment, tools, and signals for any US location, behind one API and MCP server.

Here's a demo video: https://www.youtube.com/watch?v=haqO6UbUqU0

To try it, paste https://www.mireye.com/skills.md into your agent, and grab a free key at mireye.com (5,000 credits, no card). Docs are at https://docs.mireye.ai. The fastest way in is to ask the API any question about any US location. Test it on a place you know, cold and grade it against what you know.

Before Mireye I was building construction agents and hit this wall myself: my agent could reason about anything online but knew nothing about the ground under it. Then a Fortune 500 insurer told me their engineers had given up on underwriting agents for the same reason. Frontier models keep hallucinating when asked a specific question about a specific place.

My first product was a niche site-screening app. Customers tested it on places they knew and the answers held up, but nobody cared about the app. They wanted the engine underneath. Usage agreed: 311 of the 317 fields in the catalog get queried and no use case dominates. So I killed the app and started building the infrastructure instead.

Mireye is not a dataset with an API on top, because facts alone are not a decision. An agent runs the whole job through it: cited facts, a bare address enriched into owner, acreage, structures, and nearby power, tools for the operations models get wrong, and signals when something changes, like a rezoning filing. Data, enrichment, tools, signals.

The tools came from watching agents fail. We build agents on our own infra, and the same things kept breaking: an agent would eyeball a distance instead of computing it, grab the wrong parcel for an address, or burn its whole budget halfway through a batch. Each failure became something an agent can call: deterministic geometry and drive-time tools, parcel resolution, a quote endpoint that prices a job before it runs, and skills that package whole workflows like screening a site or underwriting an address.

The hard part surprised me. Every source has to be gathered (sometimes county by county, in whatever format each county publishes), normalized into one schema, contracted (where it comes from, what each value means, how often it refreshes), and then kept fresh forever. We run that loop for 366 fields today, served multi-tenant from one index, and every source fought back differently. Maryland publishes a dataset literally titled "Hidden Property Owner Names." I filed public records requests in North Carolina because nobody indexes sewer mains.

The deeper problem is meaning. Two counties publish a field with the same name and it means different things. And the most dangerous value is null. Does it mean "no flood zone here" or "this county never mapped floods"? Put a model in front of that gap and it fills the silence with a plausible number. So we type absence. Every field returns ok, absent, or failed. Customers have told me the refusals are why they trust it.

The newest piece is on-demand indexing. Ask for a field we don't have and a long-running agent researches sources, collects the data, tests it against ground truth, and indexes it, usually within a day. I'll take a few field requests from this thread and report back with what it built.

People have built things I didn't plan for: insurance teams screening portfolios for flood, wind, and wildfire, a proptech cleaning messy listing addresses through enrichment, a wellness brand scoring street corners for poster spots, a robotics company sourcing warehouses, data center site selection, drone deployment planning, school bus routes for a city, signals for human trafficking investigations. The mission is to index every inch of the earth and make it as queryable as the web.

Pricing is public: the free tier is 5,000 credits a month, $19/month for 25,000, $99/month for 120,000, custom for enterprise.

I'd love to hear where the agents you're building touch the physical world. And I'd love it more if you run Mireye on a place you know and tell me what we got wrong.

Texas Data Center Map: See where data centers are operating or planned

2026-09-03 @ 16:10:12Points: 33Comments: 27

VC isn't VC anymore – understanding the rise of Cancer Capital

2026-09-03 @ 15:51:53Points: 177Comments: 1

Sony makes bold claim about game ownership

2026-09-03 @ 15:44:54Points: 162Comments: 218

K2 Horizon: Frontier Performance, Radically Open

2026-09-03 @ 15:36:43Points: 187Comments: 60

Grok outage

2026-09-03 @ 15:26:01Points: 153Comments: 146

Ask HN: Why are OpenAI, Claude, and Grok simultaneously down? Coincidence?

2026-09-03 @ 15:07:01Points: 253Comments: 468

.name Termination

2026-09-03 @ 14:54:39Points: 961Comments: 277

Any Human Ever – One life, drawn at random from all who have ever lived

2026-09-03 @ 14:51:10Points: 300Comments: 135

New York Times and The Athletic workers demand company scrap Kalshi deal

2026-09-03 @ 13:51:44Points: 239Comments: 185

Nvidia to Acquire Hugging Face

2026-09-03 @ 12:10:33Points: 286Comments: 91

Google Antigravity TOS: 3rd party usage can get Google account suspended

2026-09-03 @ 11:01:04Points: 208Comments: 141

Audacity 4.0

2026-09-03 @ 10:53:08Points: 935Comments: 209

Claude for Commerce Agents

2026-09-03 @ 09:37:55Points: 53Comments: 58

Pre-Release of Polars 2.0

2026-09-03 @ 06:59:08Points: 363Comments: 120

Launch HN: RonanRX (YC S26) – Personalized Peptides and GLP-1s

2026-09-02 @ 22:36:04Points: 113Comments: 80

I’m Lloyd, one of two founders of RonanRx (https://ronanrx.com/). We are building a vertically integrated pharmaceutical company with software for prescribing, telehealth, compounding, manufacturing, and delivery. We are starting with GLP-1s and peptides.

The path to RonanRx is fairly unconventional. During the pandemic, I built one of the largest mask manufacturing factories in the US. We could make a million masks in a day. We converted raw polypropylene pellets into finished pallets of masks.

I had a background in software from my YC W10 company, so we took a software approach to building our factory. We used machine learning and computer vision to optimize production. We also vertically integrated almost everything. It worked. We built an efficient manufacturing operation and grew the business to 50 million dollars in revenue. Then people actually stopped caring about masks. Fair enough.

Around the same time, I decided to try and lose the weight I had gained while building the factory. I ate nothing but chicken for six months. While this diet got some results, I plateaued. My doctor suggested tirzepatide, a GLP-1 medication.

For me, losing weight was only the beginning. "Food noise" was gone. I showed less interest in other compulsive behavior. I stopped scrolling Instagram and quit biting my nails. But that was just the beginning. I was born with a congenital heart defect called aortic stenosis. My whole life doctors told me I'd need open heart surgery in my 40s (I am 45 now). After just 18 months using tirzepatide, my cardiologist’s began to think (and still thinks) my surgery could be pushed back until I am 70 or 80.

This was all happening when I was deciding what to work on next. I wanted to keep working on manufacturing. I didn't want to build another product that could be replicated by a frontier model. Pharmaceutical manufacturing was the best combination of digital, physical, biological, and regulatory infrastructure I could find. The thing that bothered me was how disconnected all of the pieces were: telehealth, EHR, prescriptions, dispensing software, production, shipping. No one company has it all.

GLP-1s come in a handful of predefined doses, but patients obviously aren't standardized: they respond differently, lose weight at different rates, experience different side effects, and may need very different doses. Compounding pharmacies can fill customized prescriptions, but they are not built like software companies. Workflows are manual, fragmented, and disconnected from the patient’s data. It's our goal to connect those pieces with RonanRx.

Patients either come to us directly or are referred by a physician. Once a patient is in our system, we collect medical records, current meds, labs, and data from wearables. Our software follows the prescription through drug formulation, compounding, quality testing, and drug dispensing and distribution.

The most interesting feature is the feedback loop. As the patient is undergoing treatment, their response becomes data that can be used by their doctor to modify the treatment. We keep the doctor in the feedback loop.

We make money by selling drugs we manufacture. Because people can buy directly from us, their price is usually 3x-10x more affordable. We can do this because we start at the molecule and own the entire stack from manufacturing through prescribing, dispensing, and delivery, instead of paying a chain of middlemen at every step.

We are beginning with GLP-1s and peptides since this was where I personally experienced the issue; however, we are more interested in the potential of patient-specific pharmaceutical manufacturing.

We would love your feedback, especially if you have built pharmacy, manufacturing, clinical infrastructure, EHRs, or any other regulated software. There are a lot of assumptions in this model that should be tested.

Muse Spark 1.3

2026-09-02 @ 19:35:04Points: 676Comments: 438

Static Allocation, Constant Work

2026-09-02 @ 17:30:55Points: 79Comments: 13

Gemini 3.8 Flash and 3.8 Flash Cyber

2026-09-02 @ 15:12:40Points: 1139Comments: 645

Google avoids a breakup of its ad tech business

2026-09-02 @ 14:46:16Points: 464Comments: 336

The browser's main thread is expensive

2026-09-01 @ 14:00:15Points: 341Comments: 121

Invisible Companies

2026-09-01 @ 12:48:40Points: 154Comments: 56

Fish bad, sugar good and other medieval ideas about food

2026-08-31 @ 19:14:01Points: 91Comments: 70

The Computer Museum of America reclamation project

2026-08-31 @ 16:15:37Points: 109Comments: 42

Amazon Stonehenge: Parque Arqueológico do Solstício

2026-08-31 @ 03:37:12Points: 53Comments: 16

Intrusive linked lists (2019)

2026-08-31 @ 03:28:32Points: 78Comments: 53

My BC-250 Journey (With 40 CUs Unlocked)

2026-08-30 @ 14:14:58Points: 17Comments: 11

What I Learned from My Mom (1941-2026)

2026-08-29 @ 19:52:51Points: 236Comments: 10

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